Etudes en cours

 

Etude Sponsor / Promoteur Titre du projet
ADAPT CHU Limoges Adjunctive DobutAmine in sePtic cardiomyopathy with Tissue hypoperfusion: a randomized controlled multi-center trial
ADRESS PILOT CHU Dijon Bourgogne Alpha 2 agonist dexmedetomidine for sympathetic Deactivation in REfractory Septic Shock
AFTER ROSC CHU Nantes Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Out of Hospital Cardiac Arrest (AfterROSC1)
AMIDIAL ICU CHU Reims Prescription Strategies of Amikacin in Intensive Care Patients on Renal Replacement Therapy: an Observational Prospective Multicenter Study
AR-301-002 ARIDIS Pharmaceuticals Placebo-controlled, double-blind, randomized study of Salvecin as adjunct therapy to antibiotics in the treatment of S.aureus pneumonia
ARBs CORONA II University of British Columbia Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan on Outcomes of Coronavirus Infection?
ASTONISH MOT-C-203 INOTREM Efficacy, safety and tolerability of Nangibotide in Patients with Septic Shock
BICARICU-2 CHU Montpellier Traitement adjuvant des acidoses métaboliques et ou mixtes sévères avec insuffisance rénale aigüe modérée à sévère par bicarbonate de sodium : étude prospective multicentrique randomisée et contrôlée
CF301 ContraFect Corporation A Multicenter, Multinational, Double-Blind, Randomized, Placebo-Controlled Comparative Study of the Safety, Tolerability, Efficacy, and Pharmacokinetics of CF-301 vs. Placebo on a Background of Standard-of-Care Antibacterial Therapy for the Treatment of Adult Patients with Staphylococcus Aureus Bloodstream Infections Including Right-Sided Endocarditis
COVID-ICU Centre hospitalier la Pitié Salpêtrière Infection à Covid-19 en réanimation
Etude de cohorte multicentrique
DISCOVERY Inserm Multicenter, adaptative, randomized trial of safety and efficacy on treatments of Covid-19 in hospitalized adults
EARLY MOB    
ESSENTIAL MOT-C204 INOTREM Efficacy and Safety Study of Nangibotide in Patients With COVID-19 Receiving Ventilatory Support and Features of Systemic Inflammation.
EVERDAC CHR Orléans et CHU Tours Insertion systématique précoce d’un cathéter artériel versus insertion différée au cours de l’insuffisance circulatoire aiguë (PHRC National 2017)
FIXATUB Vendée CHD Comparison of Two Methods of Securing Endotracheal Tubes in Intensive Care : Elastic Adhesive Strips vs Lace In A Protective Sheath
FLUNEXT CHRU Lille Validation de l'efficacité anti-grippale de molécules repositionnées sur la base de leur signature cellulaire transcriptomique antagoniste de celles liées à l'infection par le virus Influenza A
FRENCH COVID-19 Inserm Protocole de caractérisation clinique des infections émergentes sévères
HIGH FLOW ACRF Assistance Publique - Hôpitaux de Paris Use of Nasal High Flow Oxygen During Breaks of Non-invasive Ventilation for Patients With Hypercapnic Respiratory Failure
IDAST Assistance Public - Hopitaux de Paris Optimisation personnalisée du traitement antibiotique des patients présentant un sepsis pulmonaire par l'utilisation combinée de test rapide d'identification bactérienne et de son antibiogramme, et de modélisation pharmacokinétique/pharmacodynamique
ILIAD-7 REVIMMUNE Etude multi cohorte multicentrique randomisée en double aveugle contrôlée versus placebo évaluant le traitement de l'interleukine-7 humaine recombinante (CYT107) pour améliorer les résultats cliniques chez les patients lymphopéniques infectés par le coronavirus
IOXSOR CHU Angers Measurement of Iohexol Plasma Clearance in Patients Leaving ICU After Acute Renal Failure (IOXSOR)
PREDIGAZ CHR Orléans Prediction of Arterial Lactate and Blood Gas Values Through the Analysis of Central Venous Blood (PREDIGAZ)
PROCOCO Assistance Public - Hopitaux de Paris Corticothérapie guidée par le dosage du procollagène 3 au cours des syndromes de détresse respiratoire aiguë persistants
PTSD Réa CH Chartres Reducing Post-traumatic Stress Disorder After ICU Discharge With the IPREA3 Program (PTSD-REA)
RECORDS AP-HP Hopital Raymond Poincaré, CIC 1429 Centre d'Investigation Clinique Rapid rEcognition of Corticosteroid Resistant or sentive in Sepsis
RECOVIDS CHU Dijon Bourgogne Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status (RECOVIDS)
REMAP-CAP MJM Bonten, UMC Utrecht Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)
REVIVAL AM Pharma Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI
SEPSIR CHU Angers Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock (SEPSIR)
SESAR CHRU Clermont Ferrand SEvoflurane for Sedation in ARds (SESAR)
SOHO CHU Poitiers Impact on mortality of a strategy including Standard Oxygen versus High flow nasal cannula Oxygen therapy in patients with acute respiratory failure: a Prospective, Randomized Controlled Trial.
TAVEM 2 CHRU Lille Antimicrbiol Treatment in Patients with Ventilator Associated Tracheotomitis (TAVeM2)
TRACH WEAN   Prise en charge des patients trachéotomisés pour un sevrage ventilatoire en réanimation, de la mise en place de la trachéotomie à la décanulation : étude prospective observationnelle de cohorte multicentrique

 

CRICS-TRIGGERSEP « Clinical Research in Intensive Care and Sepsis - TRIal Group for Global Evaluation and Research in SEPsis »

CIC1435 – CHU de Limoges

2 Avenue Martin Luther King – 87042 Limoges cedex - FRANCE
Contact : Anne CLAUZEL - Chef de projet - courriel - +33 2 18 37 08 99.